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Newsletter December 2012

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News: Shape matters in DNA nanoparticle therapy
Researchers from The Johns Hopkins University and Northwestern University have discovered how to control the shape of nanoparticles that move DNA through the body and have shown that the shapes of these carriers may make a big difference in how well they work in treating cancer and other diseases. The results of this study, which were published in the journal Advanced Materials ("Plasmid-Templated Shape Control of Condensed DNA–Block Copolymer Nanoparticles"), are also noteworthy because this gene therapy technique does not use a virus to carry DNA into cells. “These nanoparticles could become a safer and more effective delivery vehicle for gene therapy targeting cancer and other illnesses than can be treated with gene medicine,” said Hai-Quan Mao, of Johns Hopkins, who, together with Erik Luijten of Northwestern, led this research.

The CliniBook: clinical gene transfer state-of-the-art
This book provides a reference for state-of-the-art gene transfer technology as of 2012 and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with ethical, safety and legal issues, which are discussed. This book is ideal for researchers, clinical investigarors, post-graduate fellows, undergraduate scholars, regulators, patients' advocacy groups and policy-makers, looking for state-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - for gene transfer intended for clinical translation.

Gene Therapy Net members can order now for a reduced price of 80 € (normal price 95 €).

Conference: Cell & Gene Therapy Forum 2013
Register for the Cell & Gene Therapy Forum 2013, the most successful edition in the meeting's 9-year history. We expect well over 300 attendees for this specific conference, with 600+ biologics decision-makers attending the Phacilitate Washington 2013 meeting in total (including the Washington Vaccine Forum and Protein Therapeutics Forum).

Take a look at the event website for more details As you'll see we have extensive regulatory coverage over the course of the three days, in plenary as well as in-depth workshop formats. A few of the confirmed regulatory experts attending include:
- Dr Celia M. Witten, Director,  Office of Cellular, Tissue & Gene Therapy (OCTGT), CBER, US Food & Drug Administration
- Dr Maria Cristina Galli, Chair of the Gene Therapy Working Party, CAT/EMA
- Dr Gopalan Narayanan, Expert Medical Assessor, Medicines & Healthcare Products Regulatory Agency (MHRA), UK; Member of the CAT & SAWP, EMA
- Steven S. Oh, PhD, Team Lead, Device & Combination Product, OCTGT, CBER, US Food & Drug Administration
- Dan Takefman, PhD, Chief, Gene Therapy Branch. Division of Cellular & Gene Therapies, CBER, US Food & Drug Administration
- Anthony Ridgway, PhD, Senior Regulatory Scientist, Office of the Director, CERB, BGTD, Health Canada
- Edmund Mickunas, Vice President, Regulatory Affairs, Advanced Cell Technology, Inc
- Alice Varga, Vice President of Regulatory Affairs & Quality Assurance, OXiGENE, Inc; Independent Consultant
- Dr Joyce Frey-Vasconcells, Regulatory Expert, Frey-Vasconcells Consulting, LLC
- Dr Chris Holloway, Group Director of Regulatory Affairs & CSO, ERA Consulting Group
- Dr Christopher Bravery, Director, Consulting on Advanced Biologicals Ltd

Gene Therapy Net Members save 10% on 3 day conference fees. Simply visit:
and enter promotional code CTN to claim the 10% discount

- 28 - 30 January 2013, Phacilitate 9th Annual Cell & Gene Therapy Forum 2013, Washington DC, MD
- 13 - 15 February 2013, Gene Transfer Technologies into Multicellular Eukaryotes, Vienna, Austria
- 28 February - 2 March 2013, 19th Annual Meeting German Society for Gene Therapy (DG-GT e.V.), Munich, Germany
- 15 - 16 March 2013, Spring Symposium of the Netherlands Society of Gene & Cell Therapy (NVGCT), Lunteren, The Netherlands
- 22 March 2013, French Society of Cell and Gene Therapy (SFTCG) Annual Congress 2013, Paris, France
- 17 - 19 April 2013, Annual conference of the British Society for Gene Therapy (BSGT), London, UK
- 22 April 2013, 8th Annual Conference of The Israeli Society of Gene Therapy (ISGCT), Jerusalem, Israel
- 22 - 25 April 2013, International Society for Cellular Therapy (ISCT) 19th Annual Meeting, Auckland, New Zealand
- 8 – 10 May 2013, 8th Australasian Gene Therapy Society Meeting (AGTS), Sydney, Australia
- 15 – 18 May 2013, American Society of Gene and Cell Therapy (ASGCT) 16th Annual Meeting, Salt Lake City, Utah
- 4 – 6 July 2013, The 19th Annual Meeting of the Japan Society of Gene Therapy (JSGT), Okayama, Japan
- 24 – 28 October 2013, VII Congress of the Spanish Society of Gene (SETGyC) and Cell Therapy, and XXI Congress of the European Society of Gene and Cell Therapy (ESGCT), Madrid, Spain


Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network in the exchange of gene therapy information and breaking news items. Visitors can keep track of the latest scientific papers, conference announcements, gene therapy jobs, regulations and guidelines. Other information websites created and maintained by the owner of Gene Therapy Net are Dengue Virus Net, Influenza Virus Net and Chikungunya Virus Net.
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