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Newsletter July 2016

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News: Gene-therapy trials must proceed with caution
The perils of the past must not be allowed to happen again. Jesse Gelsinger was 18 and healthy when he died in 1999 during a gene-therapy experiment. He had a condition called ornithine transcarbamylase deficiency (OTC), but it was under control through a combination of diet and medication. Like others with the disorder, Gelsinger lacked a functional enzyme involved in breaking down ammonia, a waste product of protein metabolism that becomes toxic when its levels become too high. The gene therapy that he received used a viral vector to introduce a normal gene for the enzyme. Gene therapy remains an obvious route to treat OTC. Simply adding the missing gene has been shown to repair metabolism in mice. But the memory of what happened to Gelsinger has slowed progress in gene therapy for any condition.

News: Federal advisory committee greenlights first CRISPR clinical trial
CRISPR, the genome-editing technology that has taken biomedical science by storm, is finally nearing human trials. On 21 June, an advisory committee at the US National Institutes of Health (NIH) approved a proposal to use CRISPR–Cas9 to help augment cancer therapies that rely on enlisting a patient’s T cells, a type of immune cell. “Cell therapies for cancer are so promising but the majority of people who get these therapies have a disease that relapses,” says study leader Edward Stadtmauer, a physician at the University of Pennsylvania in Philadelphia. Gene editing could improve such treatments and eliminate some of their vulnerabilities to cancer and the body’s immune system, he says.

Conference: Adoptive T-Cell Therapy Summit Europe 2016
Welcome to the highly anticipated Adoptive T-Cell Therapy Summit Europe Edition to be in London. The only conference in Europe dedicated specifically to the 3 core Adoptive T-Cell Therapies we will give you access to the very latest clinical progress and exclusive case studies. Join us and hear experts discuss and debate the most exciting findings, case studies, keynote presentations and clinical trials in an immersive environment coupled with unrivalled networking opportunities with industry leaders.

Website: www.tcellsummit.com
Date: 10-11th October 2016
Location: London


Conferences: 2nd Annual Cell & Gene Therapy Congress
Oxford Global are proud to present the 2nd Annual Cell and Gene Therapy Congress, taking place on the 3–4 November 2016, at the Radisson Blu Portman Hotel, London, UK. Our highly anticipated event will bring together key leaders in the cell and gene therapy field to discuss updates in development, clinical trials, genome editing technologies, bioprocessing and manufacturing.

This two day conference will bring together over 250 senior level experts discussing the hottest topics, updates and challenges in the cell and gene therapy field. The conference programme consists of world-class keynote addresses, industry and academic led presentations, as well as ample 1-1 networking opportunities, creating an interactive platform for high-level scientific and business discussions. The Congress will be co-located with our prestigious 5th Annual Cell Culture & Bioprocessing and 3rd Annual Stem Cell Congresses.

Contact Guillaume Alonso on This email address is being protected from spambots. You need JavaScript enabled to view it. and quote CGT16M2 to claim for a special discount!


- 28 – 30 July 2016, The 22th Annual Meeting of the Japan Society of Gene Therapy (JSGT), Tokyo, Japan
- 18 – 19 August 2016, Gene Therapy Bioproduction conference, Boston, MA
- 12 -13 September 2016, 3rd Cell & Gene Therapy Conference, Boston, MA
- 14 -16 September 2016, 22th Annual Meeting of the German Society for Gene Therapy (DG-GT e.V.), Heidelberg, Germany
- 20 -21 September 2016, Second Annual Gene Therapy Breakthroughs, Boston, MA
- 21 -22 September 2016, Phacilitate's Cell & Gene Therapy Europe, Berlin, Germany
- 23 -24 September 2016, 1st Congress of the Hellenic Society of Gene Therapy and Regenerative Medicine, Thessaloniki, Greece
- 1 - 5 October 2016, International Meeting on Replicating Oncolytic Virus Therapeutics, Vancouver, Canada
- 5 – 7 October 2016, Cell & Gene Therapy BioProcessing & Commercialization meeting, Boston, MA
- 10 – 11 October 2016, Adoptive T-Cell Therapy Summit Europe 2016, London, UK
- 18 – 21 October 2016, XXIV Congress of the European Society of Gene and Cell Therapy (ESGCT) and the International Society for Stem Cell Research, Florence, Italy
- 21 October 2016, Second European debate on Germline Gene Editing at ESGCT-ISSCR Congress, Florence, Italy
- 3 - 4 November 2016, 2nd Annual Cell & Gene Therapy Congress 2016, London, UK
- 16 – 18 November 2016, 15th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases, Sonoma, California
- 29 - 30 November 2016, Cell Therapy Manufacturing & Gene Therapy Congress, Amsterdam, the Netherlands
- 6 - 7 February 2017, 2nd Annual Genome Editing & Engineering Conference, San Diego, CA
- 6 - 8 March 2017, International Society for BioProcess Technology 7th Spring Meeting - Viral vectors and vaccines, Washington, DC
- 16 - 17 March 2017, Spring Symposium of the Netherlands Society of Gene & Cell Therapy (NVGCT), Lunteren, The Netherlands
- 29 - 30 March 2017, 19th International Conference on Cell and Gene Therapy - ICCGT 2017, Singapore
- 19 - 21 April 2017, Annual conference of the British Society for Gene and Cell Therapy (BSGCT), Cardiff, Wales, UK
- 3 - 6 May 2017,International Society for Cellular Therapy (ISCT) 23th Annual Meeting, London, UK
- 10 - 13 May 2017, American Society of Gene and Cell Therapy (ASGCT) 20th Annual Meeting, Washington, DC
- 14 - 19 May 2017, Gordon Research Conference: Virusses & Cells, Lucca, Italy
- 24 - 26 May 2017, 10th Australasian Gene Therapy Society Meeting (AGCTS), Sydney, Australia
- 27 - 28 November 2017, 19th International Conference on Cell and Gene Therapy - ICCGT 2017, Istanbul, Turkey


Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network in the exchange of gene therapy information and breaking news items. Visitors can keep track of the latest scientific papers, conference announcements, gene therapy jobs, regulations and guidelines. Other information websites created and maintained by the owner of Gene Therapy Net are Dengue Virus Net, Influenza Virus Net, Ebola Virus Net, Chikungunya Virus Net and Zika Virus Net.
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