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Newsletter May 2010

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News: Dead as Doornail Gene Therapy Revival Spurs Genzyme
Five years ago, doctors drilled a hole into Jean Erickson’s skull, pushed in a needle and injected a cold virus modified to help transport a gene into her brain. The gene’s job was to create a mini-factory within her brain cells to pump out dopamine, a chemical that regulates physical movement. Since then, Erickson has lived more comfortably with Parkinson’s disease, a disorder that robs patients of mobility. “I stopped freezing up,” said Erickson, 71, a former pre- school director who lives in Castro Valley, California.
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News: New Gene Therapy Breakthrough in Humans is Result of Research Pioneered at OHSU's Primate Center
A promising gene therapy method first developed through animal studies at Oregon Health & Science University has now been successfully tested using human cells. Today, the scientific journal Nature published results of a study conducted at Newcastle University in the United Kingdom where a nucleus from one embryo was transferred to another. It is believed that by using this method of gene transfer, genetic diseases carried in cell mitochondria might be prevented, and maternally-based diseases that are frequently passed from generation to generation could be halted.
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News: The NIH and the FDA Joint Leadership Council: Stakeholders Meeting; Request for Comments
The Food and Drug Administration (FDA) is announcing a public meeting, in conjunction with the National Institutes of Health (NIH), to solicit comments from interested persons on how the agencies can more effectively collaborate to advance the translation of biomedical research discoveries into approved diagnostics and therapies as well as promote science to enhance the evaluation tools used for regulatory review. A newly formed NIH-FDA Joint Leadership Council will help ensure that regulatory considerations form an increasing component of biomedical research planning, and that the latest science is integrated into the regulatory review process. The public meeting will be held on June 2, 2010, from 8:30 a.m. to 12:30 p.m. Persons interested in attending the meeting must register by Wednesday, May 26, 2010, at 5 p.m. e.s.t.
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Members Discount: Download files and save up to 33%
Gene Therapy Net members can download interesting files and receive serious discounts. For example, download all questions, answers and explanation of the Gene Therapy Multiple Choice Quiz, including basic, intermediate and advanced difficulty level. The Word file is ideal study material!
You can also download the high resolution jpg image as well as the original powerpoint file of the figure: A comparison of different viral vectors in use for gene therapy: overview of their advantages and disadvantages. The powerpoint file can be used in your own presentations or for educational purposes.

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Conference: Phacilitate’s 9th annual European Vaccine Forum
Phacilitate’s 9th annual European Vaccine Forum will take place in Barcelona in June 2010. It will once again run in parallel to the Active Immunotherapeutics Forum – sharing some plenary sessions and all networking opportunities.
The Barcelona Vaccine Forum provides an invaluable opportunity for leaders from across the vaccines sector to discuss their latest progress in overcoming core clinical, regulatory, manufacturing and business development challenges. The focus is mainly on prophylactic vaccines and related technologies, such as delivery systems and adjuvants. Detailed strategic analysis of global vaccine market opportunities, trends and challenges complete the programme.
The Active Immunotherapeutics Forum provides a unique annual meeting place for senior level figures driving the development of these technologies into clinically effective, cost-effective products that are acceptable to the regulator. Therapeutic vaccines against a variety of disease targets, as well as other immune modulating approaches, are covered, with the emphasis on how clinical, regulatory and manufacturing challenges are being overcome.

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Conferences
- 17 - 18 May 2010, ASGCT Clinical Trials Training Course, Washington DC, MD
- 19 - 23 May 2010, American Society of Gene and Cell Therapy (ASGCT) 13th Annual Meeting, Washington DC, MD
- 23 - 26 May 2010, International Society for Cellular Therapy (ISCT) 16th Annual Meeting, Philadelphia, PA
- 13 - 15 June 2010, The 9th Annual Congress of La Société Francophone de Thérapie Cellulaire et Génique (SFTCG), Paris, France
- 26 - 29 June 2010, 3nd International symposium on Cellular Delivery of Therapeutic Macromolecules, Cardiff, UK
- 1 - 3 July 2010, The 16th Annual Meeting of the Japan Society of Gene Therapy (JSGT), Tochigi-ken Sougou Bunka Center, Utsunomiya-city Tochigi, Japan
- 26 August - 4 September 2010, Viral Vectors in Gene Therapy: Applications and Novel Production Methods, A.I. Virtanen Institute, Kuopio, Finland
- 6 - 9 October 2010, 17th Annual Meeting German Society for Gene Therapy (DG-GT e.V.), Munich, LMU Campus Grosshadern, Germany
- 22 - 25 October 2010, European Society of Gene and Cell Therapy (ESGCT) 18th Annual Congress, Milan, Italy
- 17 - 19 November 2010, 9th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases. Focus Topic: Gene Expression, Sonoma, CA
- 24 - 26 January 2011, Phacilitate 7th Annual Cell & Gene Therapy Forum 2011, Washington DC, MD
- 4 - 6 May 2011, Australasian Gene Therapy Society (AGTS) 7th Meeting, Melbourne, Australia
- 18 - 22 May 2011, American Society of Gene and Cell Therapy (ASGCT) 14th Annual Meeting, Seattle, WA
- 29 May - 2 June 2011, Gordon Research Conference: Virusses & Cells, Lucca (Barga), Italy

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Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network in the exchange of gene therapy information and breaking news items. Visitors can keep track of the latest scientific papers, conference announcements, gene therapy jobs, regulations and guidelines, www.genetherapynet.com
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