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Newsletter November 2016

News: Researchers take step toward gene therapy for sickle cell disease
A team of researchers at the Stanford University School of Medicine has used a gene-editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder. The team went on to demonstrate that the mended cells could make a functioning hemoglobin molecule, which carries oxygen in normal red blood cells, and then successfully transplanted the stem cells into mice. The researchers say the study represents a proof of concept for the repair of blood-borne genetic diseases, such as sickle cell disease and thalassemia.

News: Gene therapy for blistering skin disease appears to enhance healing in clinical trial
Grafting sheets of a patient’s genetically corrected skin to open wounds caused by the blistering skin disease epidermolysis bullosa appears to be well-tolerated and improves wound healing, according to a phase-1 clinical trial conducted by researchers at the Stanford University School of Medicine. The results mark the first time that skin-based gene therapy has been demonstrated to be safe and effective in patients. The findings will be published Nov. 1 in JAMA. Associate professors of dermatology Peter Marinkovich, MD, and Jean Tang, MD, PhD, share senior authorship of the study. Senior scientist Zurab Siprashvili, PhD, is the lead author.

News: HIV Cure: Portable 'Gene Therapy In A Box' A Breakthrough In Fight Against AIDS, Cancer?
Human Immunodeficiency Syndrome, better known as the HIV virus is one of the world's most notorious sexually-transmitted diseases. If left untreated, it can lead to AIDS or Acquired Immunodeficiency Syndrome. Going back to its history, HIV infection has existed in the US at least since the mid-to-late 1970s. Recently, it has been found that gene therapy can now be made possible even for the poorest of countries. Through the help of a handheld portable device that has been discovered, medical personnel can manipulate a patient's blood to carry out potential new medications for cancer, HIV and other types of diseases.

- 16 – 18 November 2016, 15th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases, Sonoma, California
- 5 - 7 December 2016, CRISPR Summit USA, Boston, MA
- 29 - 30 November 2016, Cell Therapy Manufacturing & Gene Therapy Congress, Amsterdam, the Netherlands
- 6 - 7 February 2017, 2nd Annual Genome Editing & Engineering Conference, San Diego, CA
- 6 - 8 March 2017, International Society for BioProcess Technology 7th Spring Meeting - Viral vectors and vaccines, Washington, DC
- 16 - 17 March 2017, Spring Symposium of the Netherlands Society of Gene & Cell Therapy (NVGCT), Lunteren, The Netherlands
- 17 March 2017, British Society for Gene and Cell Therapy (BSGCT) Public Engagement 2017, Oxford, UK
- 27 - 28 March 2017, 6th International Conference and Exhibition on Cell and Gene Therapy, Madrid, Spain
- 29 - 30 March 2017, 19th International Conference on Cell and Gene Therapy - ICCGT 2017, Singapore
- 19 - 21 April 2017, Annual conference of the British Society for Gene and Cell Therapy (BSGCT), Cardiff, Wales, UK
- 3 - 6 May 2017,International Society for Cellular Therapy (ISCT) 23th Annual Meeting, London, UK
- 10 - 13 May 2017, American Society of Gene and Cell Therapy (ASGCT) 20th Annual Meeting, Washington, DC
- 14 - 19 May 2017, Gordon Research Conference: Virusses & Cells, Lucca, Italy
- 17 - 19 May 2017, World Advanced Therapies and Regenerative Medicine Congress 2017, London, UK
- 24 - 26 May 2017, 10th Australasian Gene Therapy Society Meeting (AGCTS), Sydney, Australia
- 17 – 20 October 2017, XXV Congress of the European Society of Gene and Cell Therapy (ESGCT), Berlin, Germany


Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network in the exchange of gene therapy information and breaking news items. Visitors can keep track of the latest scientific papers, conference announcements, gene therapy jobs, regulations and guidelines. Other information websites created and maintained by the owner of Gene Therapy Net are Dengue Virus Net, Influenza Virus Net, Ebola Virus Net, Chikungunya Virus Net and Zika Virus Net.
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