New and Updated Clinical Gene Therapy Trials
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Gene Transfer Clinical Trial for Krabbe Disease
Jan 5, 2021 | 18:00 pmCondition: Krabbe DiseaseIntervention: Biological: FBX-101Sponsor: Forge Biologics, IncNot yet recruiting
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GDNF Gene Therapy for Multiple System Atrophy
Dec 22, 2020 | 18:00 pmCondition: Multiple System AtrophyInterventions: Biological: AAV2-GDNF gene therapy; Procedure: Sham (Placebo) SurgerySponsor: Brain Neurotherapy Bio, Inc.Not yet recruiting
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Gene Therapy Follow up for Subjects Previously Enrolled in NCI Genitourinary Malignancies Branch or Experimental Transplantation and Immunology Branch Studies
Feb 12, 2020 | 18:00 pmConditions: Cervical Intraepithelial Neoplasia; Cervical Neoplasms; Oropharyngeal Neoplasms; Squamous Intraepithelial Lesions of the Cervix; Hematologic MalignaciesIntervention: Sponsor: National Cancer Institute (NCI)Recruiting
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Gene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A
Jan 28, 2019 | 18:00 pmCondition: Hemophilia AIntervention: Biological: Auto CD34+PBSC, transduced with a lentiviral vector encoding the B domain deleted from of human coagulation factor VIIISponsor: Parameswaran HariRecruiting
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Gene Therapy for Achromatopsia (CNGA3)
Nov 29, 2018 | 18:00 pmCondition: AchromatopsiaIntervention: Biological: AAV- CNGA3Sponsors: MeiraGTx UK II Ltd; Janssen Research & Development, LLCRecruiting
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Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning
Oct 17, 2017 | 18:00 pmConditions: Severe Combined Immunodeficiency, X Linked; Gene TherapyIntervention: Biological: autologous CD34+ cell transduced with G2SCID vectorSponsor: David WilliamsRecruiting
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Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials
Dec 12, 2014 | 18:00 pmConditions: Pediatric Cancers; Hematologic Malignancies; Solid TumorsIntervention: Sponsor: National Cancer Institute (NCI)Recruiting
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Long-Term Follow-Up of Recipient of Gene Transfer Research
Dec 14, 2011 | 18:00 pmConditions: Retroviridae Infections; CancerInterventions: Other: Blood Tests; Behavioral: QuestionnairesSponsors: M.D. Anderson Cancer Center; National Center for Research Resources (NCRR); National Cancer Institute (NCI); ZiopharmRecruiting
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Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
Mar 1, 2011 | 18:00 pmCondition: X-Linked Severe Combined Immune Deficiency (XSCID)Interventions: Drug: Palifermin; Drug: Busulfan; Biological: Ex vivo culture and transduction of the patient's autologous CD34+ HSC with lentivirus vector VSV-G pseudotyped CL20- 4i-EF1a-hyc-OPT vectorSponsor: National Institute of Allergy and Infectious Diseases (NIAID)Recruiting
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Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies
Mar 22, 2007 | 17:00 pmConditions: Prostate Cancer; Liver Cancer; Breast Cancer; Colon Cancer; Lung CancerIntervention: Sponsor: National Cancer Institute (NCI)Recruiting
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