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Newsletter June 2021

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News: Decades after a tragic failure, gene therapy successfully treats a rare liver disease
Twenty-two years ago, one of scientists’ first attempts at gene therapy ended in tragedy when a young man died. The story of Jesse Gelsinger, who had a rare liver disorder, became a textbook example of irresponsible medical research. For years, the case hobbled efforts to treat diseases by adding new DNA to a sick person’s cells. Now, a fresh effort to cure Gelsinger’s disease is bearing fruit, in the latest sign of the field’s resurgence.
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Webinar: Develop a Collaborative Delivery Network for Cell and Gene Therapies
With more than 2,600 cell and gene therapy (CGT) clinical trials currently being undertaken worldwide, the potential product approvals between 2022 and 2027 could be as high as 300 to 400. That means the groundwork for seamless cell and gene therapy care delivery needs to be laid now.
With many stakeholders involved in the complex CGT treatment journey, pharma needs to develop a collaborative plan, prepare a skilled workforce, and be ready to scale up rapidly.
Experts from J&J, Microsoft, Center for Breakthrough Medicines, Marken and EY come together in this webinar to discuss developing CGT manufacturing models and interconnected supply networks, to deliver an excellent patient experience.
Tune in live to this webinar on Tuesday June 15, or sign up to receive the recording here.

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Conference: 2nd Gene Therapy Immunogenicity
The 2nd Gene Therapy Immunogenicity Summit, August 3-5, 2021, is the industry’s definitive forum enabling you to better modulate, measure and predict immune response to your gene therapy candidate.
In the context of ever-increasing gene therapy clinical activity and uncertainty around immunogenicity challenges, the Gene Therapy Immunogenicity Summit will unite large pharma and innovative biotechs to ensure that you’re up to speed on the latest approaches to predict, measure and overcome every immunogenicity challenge you encounter.
Focused specifically on examining gene therapy immunogenicity, this event will enable you to learn how to evaluate and overcome pre-existing immunity to AAV vectors, understand how immune-modulatory approaches could enable re-dosing and learn the reality of regulatory expectations around immunological assays.
Incorporating insights from leading immunological, bioanalytical and translational experts, this is your opportunity to gain extensive technical information on the contrasts between immunogenicity encountered across organs and administration routes, how models can be enhanced to enable comparative immunology between species and what the latest clinical data tells us about how to adapt existing approaches to address immunogenicity.

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Conference: 13th Annual The Bioprocessing Summit
The Bioprocessing Summit, recognized as the premier forum for industry leaders to share the latest research in bioprocess R&D, scale-up, quality and analytics, will return to Boston on August 16-19 with a virtual feed for those who cannot attend in-person. The new hybrid event model will give you the option to experience the summit in-person or online. As we navigate the new realities of conferences and gatherings you can still count on CHI’s commitment to deliver quality content and facilitated networking opportunities to help achieve your research goals.
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- 15 - 17 June 2021, 2nd RNAi- Based Therapeutics Summit, Online event
- 28 - 30 June 2021, 3rd Annual Blood-Brain Barrier Summit - Exploring CNS Gene Therapy & New Generation Vectors, Online event
- 13 - 15 July 2021, Epigenetic Therapeutic Targets Summit, Online event
- 13 - 15 July 2021, mRNA-Based Therapeutics Summit, Online event
- 19 - 21 July 2021, 2nd Gene Therapy for Neurological Disorders Europe, Online event
- 27 - 29 July 2021, Gamma Delta T Therapies Summit, Online event
- 3 - 5 August 2021, 2nd Gene Therapy Immunogenicity Summit, Online event
- 16 - 19 August 2021, 13th Annual The Bioprocessing Summit, Boston, MA
- 25 - 27 August 2021, World Orphan Drug Congress USA, Maryland, USA
- 30 August - 2 September 2021, 6th CAR-TCR Summit, Online event
- 7 - 9 September 2021, Next Generation Cancer Vaccine Development Summit, Online event
- 14 - 16 September 2021, Gene Therapy for Metabolic Disorders Summit, Online event
- 21 - 22 September 2021, Formulation & Delivery UK: Gene and Cell Therapies, London, UK
- 21 - 23 September 2021, 2nd Gene Therapy for Ophthalmic Disorders, Online event
- 22 - 23 September 2021, Oligonucleotide Therapeutics and Delivery conference, London, UK
- 28 - 29 September 2021, Cell & Gene Therapy USA - Reuters Event, Online event
- 12 - 13 October 2021, Pharma Europe 2021 - Cell & Gene Therapies, Barcelona, Spain
- 18 - 20 October 2021, Advancing Gene Therapy 2021, Boston, MA
- 19 - 21 October 2021, 2nd Annual Dry AMD Therapeutic Development Summit, Online event
- 19 - 21 October 2021, XXVIII Congress of the European Society of Gene and Cell Therapy (ESGCT), Online event
- 27 - 29 October 2021, World Smart Bioprocessing: Pharma 4.0 Summit, Berlin, Germany
- 10 - 11 November 2021, Pharma Manufacturing: Gene and Cell Therapies, Online event
- 16 - 17 November 2021, Onco Cell Therapy Summit (OCTS) USA 2021, Boston, MA
- 22 - 23 November 2021, Ophthalmic Drugs Conference - Gene Therapies, London, UK

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